Medications to treat various chronic diseases may hinder the body’s ability to lose heat and regulate its core temperature to optimal levels. The loss of effective thermoregulation has implications for elderly people receiving treatment for illnesses like cancer, cardiovascular, Parkinson’s disease/dementia and diabetes, particularly during hot weather, according to a […]
Étiquette : chronic
‘Humanized’ liver in mice reveals roots of chronic diseases
Yale researchers have created a functional « humanized » liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic liver diseases afflicting tens of millions of people in the United States. The findings are published Aug. 9 in the journal Cell. Chronic […]
Brain cells of males and females respond differently to chronic stress
Scientific excellence requires diversity — research conducted by men and women, by people from different backgrounds and with varied worldviews. The need for diversity extends to scientific experiments themselves, but even today the vast majority of studies in the life sciences are done on male mice only, which could harm […]
Immune cell discovery could lead to improved chronic worm treatment
Monash University researchers have uncovered why some intestinal worm infections become chronic in animal models, which could eventually lead to human vaccines and improved treatments. Parasitic worms, also called helminths, usually infect the host by living in the gut. About a quarter of the world population is afflicted with helminth […]
Scrambler therapy may offer lasting relief for chronic pain, review paper suggests
A new review paper co-authored by two Johns Hopkins pain experts suggests that scrambler therapy, a noninvasive pain treatment, can yield significant relief for approximately 80%-90% of patients with chronic pain, and it may be more effective than another noninvasive therapy: transcutaneous electrical nerve stimulation (TENS). The write-up was published […]
Gene therapy treats chronic pain by dialing down sodium
Researchers at NYU College of Dentistry’s Pain Research Center have developed a gene therapy that treats chronic pain by indirectly regulating a specific sodium ion channel, according to a new study published in the Proceedings of the National Academy of Sciences (PNAS). The innovative therapy, tested in cells and animals, […]